Histoplasmosis – Part 3123

Treatment & Drugs

Treatment usually isn’t necessary if you have a mild case of histoplasmosis. But if your symptoms are severe or if you have the chronic or disseminated forms of the disease, you’ll likely need treatment with one or more antifungal drugs. Some of these medications come in pill form, but the strongest varieties are administered intravenously.


t’s difficult to prevent exposure to the fungus that causes histoplasmosis, especially in areas where the disease is widespread. Even so, these steps can help reduce the risk of infection:

  • Avoid exposure. If your immune system is compromised, avoid renovation projects that might expose you to contaminated soil. Likewise, cave exploring and raising birds — such as pigeons or chickens — aren’t advised.
  • Spray contaminated soil. Before you work in or dig soil that’s likely to harbor the fungus that causes histoplasmosis, spray it thoroughly with water. This can help prevent spores from being released into the air. Spraying chicken coops and barns before cleaning them also can reduce your risk.
  • Use an effective face mask. One of the best ways to protect yourself from soil-borne organisms if you must work in contaminated areas or in caves known to harbor bats is to wear a respirator mask. Consult with the National Institute for Occupational Safety and Health to determine which type of mask will provide adequate protection for your level of exposure.

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About the author: Joe Fiorilli